TOPICWISE MCQ’s
Alkaloids
1)
Alkaloid belonging to benzylisoquinoline group
A. Quinine |
B.
Emetine |
C.
Physostigmine |
D. Ajmaline |
2)
A.
Ergot alkaloids |
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B.
Opium alkaloids |
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C.
Vinca alkaloids D.
Ipecac Alkaloids 3)
Hyoscamine and
scopalamine differ in their structure by presence of
|
4)
Which of the following alkaloids is derived
from aliphatic aminoacid?
A.
Connesinne |
B.
Caffeine |
C.
Atropine D.
Aconite |
5)
An
alkaloidal extract when heated with
nitric acid followed by addition of potassium hydroxide and acetone yielded
purple colour. Hence, it can be concluded to contain which of the following
alkaloid
A.
Puriene |
B.
Quinine |
C.
Tropane |
D.
Ergot |
6)
A drug used to treat malaria is………..
A. Vasaka
B.
Cinchona
C. Vinca
D. Nux vomica
7)
A snake shaped root is:
A. Ashwagandha
B. Sarpagandha
C. Aconite
D. Liquorice
8)
The pharmacological use of opium is:
A. Stimulant
B. Narcotic analgesic
C. Emetic
D. Galactagogue
9)
Diacetyl derivative
of morphine is
A.
Codeine
B.
Papaverine
C.
Heroin
D.
Thebaine
10)
Which
compound is showing the most potent analgesic
property?
A.
Codeine
B.
Papaverine
C.
Heroin
D.
Thebaine
11) Which of the following may be used as a marker compound for
standardization of Rauwolfia?
A. Ajmalicine
B. Quinine
C. Emetine
D. Lysergic acid
12) An alkaloid containing
tropolane or cycloheptatrien-ol-one ring is
A. Reserpine
B. Colchicine
C. Vincristine
D. Cocaine
13)
A heterocyclic aromatic
organic compound that consists of a Pyrimidine ring fused to
an imidazole ring is
A. Atropine
B. Vasicine
C. Strychnine
D. Caffeine
14)
Which
of the following crude drug is used to lift mood?
A. Cocoa
B. Ashwagandha
C. Cinchona
D. Solanum
15)
The
process of curing is used in Harvesting of
A. Vinca
B. Kurchi
C. Tobacco
D. Coffee
16)
Mossing
& Coppicing are practiced for cultivation & Collection of
A. Cinchona
B. Senna
C. Ashwagandha
D. Arjuna
17) Which of the following is derived from condensation of dopamine with secologanin?
A. Cephaeline
B. Quinine
C. Pilocarpine
D. Conessine
18) Ester of trimethoxycinnamic
acid is
A. Rescinnamine
B. Syrosingopine
C. Vindoline
D. Hyoscine
19)
The name St. Anthony’s fire is
associated with
A. Colchicum
B. Fenugreek
C. Ergot
D. Ephedra
20) p-dimethyl aminobenzaldehyde is used in preparation of…..
A. Mayer’s reagent
B. Van Urk’s reagent
C. Hager’s reagent
D. Gold beater’s reagent
21)
Opium capsules
are incised vertically in the afternoon with the help of specific needle like
apparatus called
A. Nushtur
B. Charphala
C. Nupur
D. Fork Knife
Biosynthesis
22) Biosynthetic origin
for emetine is
A. Lucienne |
B.
Tryptophan |
C. Tyrosine D. Isoleucine
|
23) Starting
compounds in biosynthesis of quinine include
A. Phenyl alanine and secologanine |
B.
Phenyl alanine and
geraniol |
C. Tryptophan and Secologanin |
D.
Tyrosine
and geraniol 24) Atropine is a racemic mixture of A. +,-, Hyoscyamine B. +,-, Hyoscine C. +,-, Hygrine D. +,-, Tropane 25) Opium contains salts of one of the following acid A. Meconic acid B. Lysergic acid C. Quinovic acid D. Fulvic acid |
26) Isoquinoline alkaloid
is found in:
A.
Solanum
B.
Berberis
C.
Vasaka
D.
Cocoa
27)
Caffeine is a:
A.
Tropane alkaloid
B.
Indole alkaloid
C.
Purine alkaloid
D.
Quinoline alkaloid
Standardization of herbal drugs using various type of markers with
examples.
28)
Which of the following major challenge is faced in
preparation of herbal formulation:
A.
Weighing
B.
Drying
C.
Labelling
D.
Measuring
29)
Detoxification of drugs in Ayurveda is:
A.
Drying of drugs
B.
Cultivation of drugs
C.
Reducing drug toxicity
D.
Standardization of drugs
30) Which of the
following is an NDDS of Herbal medicine?
A.
Herbal Tablet
B.
Herbal Capsule
C.
Herbal cream
D.
Herbal Liposomes
31) A
method of quantification of the biomarkers and/ or chemical markers and the
fingerprint profiles in Herbal drug research is called as ………….
A. Calibration
B. Authentication
C. Cultivation
D. Standardization
32) Most
important aspect of Standardization of crude drug is
A. Quantification of
active constituent
B. Qualitative analysis of
crude drug
C. Determining Physical
constant of drug
D. Determining the
geographical source of drug
33) The
identification, purity and quality of herbal drugs are determined by
A. References of
analytical methods given in a pharmacopoeia
B. Performing pilot studies.
C. references mentioned in
journal publications
D. comparing values obtained
by any chromatographic method.
34) Chromatography can
be used in herbal drug studies for
A. Herbal drug Cultivation
B. Herbal drug garbling
C. Herbal drug quality assurance.
D. Herbal drug Adulteration
35) The
idea of standardization and quality control of drugs can be found even in the
ancient Ayurveda texts
A. Yes
B. No
C. Maybe
D. Can’t Say.
36) A
technique in large scale employed in pharmaceutical industry in process
development, identification and detection of adulterants in herbal product and
helps in identification of pesticide content, mycotoxins and in quality control
of herbs
A. UV-Vis
B. HPTLC
C. GC-MS
D. LC-NMR
37) The purpose of a
stability testing is to provide proof on
A.
How the quality of the herbal products varies with the time under the
influence of environmental factors
B.
quality of seeds used during cultivation
C.
quality of excipients used in formulation
D.
quantity of drug adulteration.
38)
Simultaneous estimation of actives is a boon for
standardization of…….
A. Polyherbal
Formulations
B. Adulterated Drugs
C. Authenticated
Drugs
D. Indigenous Drugs.
39)
Which of the following method helps in determining shelf
life of an herbal formulation?
A. Herbal drug standardization
B. Stability testing of
Herbals
C. Herbal drug adulteration
D. Herbal drug authentication
Miscellaneous
40)
A cardiac glycoside containing drug is:
A.
Liquorice
B.
Diosgenin
C. Digitalis
D.
Fenugreek
41)
The aglycone part of a saponin is called
A.
Apigenin
B.
Conessine
C.
Sapogenin
D.
Nor conessine
42)
Monodesmosidic, bidesmosidic, etc nomenclature depends on
A.
Number of Isoprene units
B.
Number of amino acid units
C.
Number of peptides
D.
Number of Saccharide chains
43)
Liquorice contains:
A.
Pentacyclic triterpenoids
B.
Tetracyclic triterpenoids
C.
Tropane alkaloids
D.
Ouabegenin
44) Which of the following is used to commercially
to synthesize steroidal molecule?
A.
Ginseng
B.
Dioscorea
C.
Brahmi
D.
Ephedra
45)
Dried roots of Ginseng are obtained from:
A.
Panax purpurea
B.
Panax Cinnamon
C.
Panax limonis
D.
Panax ginseng
46)
Which of the following is used as a memory enhancer?
A. Cinchona
B. Brahmi
C. Aloe
D. Garlic
47) Which of the following
contains a toxic glycoprotein?
A. Castor
B. Pea
C. Oats
D. Bitter Almond
48)
Dimeric phenylpropanoids
are called:
A. Glycoproteins
B. Lignan
C. Glycoalkaloids
D. Tannins
49)
Which of the following drug is also called as St Johns’
wort:
A. Aloe
B. Hypericum
C. Rubia
D. Wild Cherry Bark
50) Which of the
following drug’s action is enhanced by interaction with Ginkgo biloba
A.
Digoxin
B.
Warfarin
C.
Penprocouman
D.
Benzodiazepine
51)
In Mass spectroscopic analysis Gallic acid shows base peak
at
A. 145
B. 125
C.170
D.189
Steriodal and Triterpenoidal glycosides
52) Triterpene
saponins are usually derivatives of
A.
β-amyrine
B.
Amino acids
C.
Lysergic acid
D.
Truxillic acid
53) The liqourice
owes most of its sweet taste to
A.
Glycyrrhizin
B.
Chalcone glycosides
C.
glabrocoumarone
D.
Isoliquiritigenin
54) Dammarol is
A.
Aglycon of
Ginsenosides
B.
Aglycon of panaxosides
C.
Glycoside of panaxosides
D.
Glycoside of Ginsenosides
55) Acetyldigitoxose is present in
A.
Lanatosides A
B.
Digoxin
C.
Digitoxin
D.
Glucoverodoxin
56) Digitalis leaves should be dried below 60 degree Celsius as its
potency decreases due to
A.
Dehydration of C-14 OH group to give inactive anhydro-form
B.
Hydrolysis of glycosides
C.
Reduction of
digitoxose
D.
Isomerization of the active compound
57) Tetracyclic and pentacyclic terpenoids are subclasses of
A.
Saponins
B.
Tannins
C.
Alkaloids
D.
Flavonoids
58) Dioscin is
A.
Steroidal Saponin
B.
Steroidal Sapogenin
C.
Pentacyclic saponin
D.
Pentacyclic saponin
59) Chikusetsusaponins are present in
A.
Ginseng
B.
Brahmi
C.
Digitalis
D.
Fenugreek
60) Hecogenin is major chemical constituent of
A.
Fenugreek
B.
Colchicum
C.
Solanum
D.
Dioscorea
61) Six member lactone ring is present in
A.
Scillarin
B.
Digitoxin
C.
Digoxin
D.
Gitaloxin
62) Scillabiose
on hydrolysis gives
A.
Rhamnose +Glucose
B.
Glucose+Glucose+Rhamnose
C.
Glucose+Glucose
D.
Rhamnose+Rhamnose
63) ___________ is preferred in
the treatment of congestive heart failure
A.
Reserpine
B.
Ephedrine
C.
Digoxin
D.
Digitoxin
64)
___________ is commonly called as Himalayan Ginseng
A.
Panax japonicus,
B.
Panax pseudoginseng
C. Panax quinquefolius
D.
Panax trifolius
65) Following compound is
A.
Scillaren A
B.
Proscillaridin A
C.
Scillaridin A
D.
Kaempferol
66) Asiaticosides are
present in
A.
Brahmi
B.
Foxglove
C.
Kurchi
D.
Ginseng
67) The glycoside present in the red
squill is known as
a.
Scilliroside
b. Citrin
c. Scillaren A
d. Proscillaridin
68) Source for bufadienolide is
A.
Squill
B.
Digitalis
C.
Centella
D.
Rhubarb
69) __________________ test is
used for identification of digitoxose sugar
A.
Keller killiani’s
B.
Legal’s
C.
Baljet’s
D.
Liebermann Burchard
70) Following is used as galactogogue
A.
Shatavari
B.
Brahmi
C.
Vasaka
D.
Tea
71)
Shatavarin I-IV are the phytoconstituents obtained from
A.
Asparagus recemosus
B.
Centella asiatica
C.
Urginea maritima
D.
Trigonella foenum graecum
72)
____________ is used as an immunomodulating agent
A.
Ginseng
B.
Ephedra
C.
Datura
D.
Kurchi
73)
Fenugreek belongs to family_______________
A.
Leguminosae
B.
Liliaceae
C.
Scrophulariaceae
D.
Apocynaceae
74) __________ of Urginea maritima are used as a source for phytoconstituents
A.
Bulbs
B. Roots & Rhizome
C. Stolons
D. Whole herb
75) Brahmi belongs
family_______________
A.
Umbelliferae
B. Acanthceae
C. Rannunculaceae
D. Solanaceae
Detailed study of Flavonoids and Coumarins
76) Aglycon of rutin is
A.
Quercetin
B.
Quercitin
C.
Cirantin
D.
Anthracene
77) Bergapten is also known as
A.
5-Methoxypsoralen
B. Panaxoside
C. 8-methylpsoralen
D. Colchicoside
78) Following structure is a
A.
Isoflavone
B.
Flavone
C.
Flavanone
D.
Flavonol
79) Buckwheat is the common name
of
A.
Fagopyrum esculentum
B. Ruta graveolens
C. Cassia angustifolia
D. Rheum emodii
80)
__________________is used to
decrease the capillary fragility
A.
Rutin
B. Psoralen
C. Emodein
D. Aloin
81) ______________ contains
furanocoumarins
A.
Psoralea corylifolia
B. Cassia angustifolia
C. Rheum emodii
D. Digitalis purpurea
82)
___________ is the most predominant flavonoid in orange peel
A.
Hesperidin
B.
Ephedrine
C.
Citric acid
D.
Pectin
83) Lignans are
A.
Biphenylpropanoid
B. Phenylalanine
C. Phenylpropene
D. Coumarins
84) Etoposide is semisynthetic
derivative of
A.
Podophyllotoxin
B. Podophyllotoxone
C. α- peltatin
D.
β-peltatin
85) Test for identification of
flavonoids
A.
Shinoda
B. Murexide
C. Vitali Morin’s
D. Salkowski
Regulatory Issues - ASU formulations, patent and proprietary medicine
and Phytopharmaceuticals
86) AYUSH introduced Rule 158(B) which made the
requirement of proof of effectiveness for licensing of a patent or proprietary
A.
ASU
medicine
B.
Phytopharmaceuticals
C.
There is no such rule
D.
AYUSH looks into standardization only
87) Ayurveda, Siddha, and
Unani (ASU) drugs are regulated under
A. Chapter
IVA of D&C Act and Rules
B.
Chapter VA of D&C Act
and Rules
C.
Schedule M
D.
Schedule R
88) Proprietary medicine
A.
Are controlled by individual
B. Are not controlled by individual
C. Don’t contain secret active ingredient
D. Controlled by Schedule M
89) Schedule T is for
A.
GMP of ASU drugs
B. Export of ASU drugs
C. Import of ASU drugs
D. Clinical trials of ASU drugs
90) Requirements on guidelines on
clinical trials for import and manufacturing of new drugs
A.
Schedule Y
B. Schedule S
C. Schedule J
D. Schedule A
91) Department of AYUSH
deals with
A. Ayurveda,
Siddha Unani and phytopharmaceuticals
B.
Only phytopharmaceuticals
C.
Only ayurvedic formulations
D.
Only unani formulations
Study of herbal
formulations & Ayurvedic formulations
92) Phytopharmaceuticals are
under the purview of __________
A.
Central Drugs Standards Control Organization
B. AYUSH
C. Wealth of India
D. Ministry of health and family welfare
93) Standard of self-
generated alcohol for Asava & Arishtas
A. Not
more than 12% v/v
B.
Not less than 12% v/v
C.
Equal to12% v/v
D.
Cannot be measured
94) Arista is prepared by
A.
Decoction of drugs is used for fermentation with jaggery
B. Fine powder of drugs is used for fermentation with jaggery
C. Decoction of drugs is used no fermentation
D. Fine powder of drugs is used no fermentation
95) Taila
A.
Have color, odor and taste of the drugs used
B. Are fermented products
C. Are Semisolid in nature
D. Is Non ayurvedic formulation
96) Sodhana is
A.
Purification
B. Standardization
C. Compression to form tablet
D. Synthesis
97) ____________ is a
semisolid preparation of drugs, prepared by addition of jaggery, sugar or sugar
candy and boiled with prescribed drug juice or decoction
A.
Avaleha
B. Churna
C. Arista
D. Asava
98) Herbal formulations
are advantageous over synthetic ones because
A. They
are comparatively safe
B.
Easy to formulate
C.
Easily available
D.
Highly stable
99) Gutika is
A.
Solid dosage form
B. Semisolid dosage form
C. Liquid dosage form
D. Fermented formulation
100)
Phytosome is different than liposome as
A.
Active chemical constituents are anchored thorough chemical
bonds to polar head.
B. Active chemical constituents are dissolved in the medium.
C. Size is small.
D. It is a NDDS formulation
101)
___________ are the powdered
forms of a substance obtained by calcination.
A.
Bhasmas
B. Ghrita
C. Avaleha
D. Churna
Glycoprotein
102)
A toxic protein, Ricin, is present in…………
A.
Oat
B.
Cabbage
C.
Pea
D.
Castor seeds
103)
Glycoproteins are ………
A.
Acetal derivatives formed when a monosaccharide reacts with
an alcohol
B.
Carbohydrate binding proteins
C.
Toxic steroidal glycosides
D.
Macromolecular complexes of lipids and proteins
104)
Botanical source of oat is…………
A.
Avena sativa
B.
Alium sativa
C.
Coriandrum sativa
D.
Pisum sativum
105)
Lectins are ………
A.
Glycoproteins
B.
Proteolytic enzymes
C.
Protein hydrolysates
D.
Lipoproteins
106)
Ricin is ………
A.
Lipoprotein
B.
Proteolytic enzyme
C.
Protein hydrolysate
D.
Type-II ribosomal inactivating protein
Glycosides
107)
Senna mainly contains…………
A.
O-type glycoside
B.
C-type glycoside
C.
S-type glycosides
D.
O-type glycosides
108)
Which drug is under the chemical class of cyanogenetic
glycoside?
A.
Bitter almond
B.
Black mustard
C.
Digitalis
D.
Rhubarb
109)
The drug showing antidepressant property …………
A.
Rhubarb
B.
Aloe
C.
Liquorice
D.
St. John’s Wort
110)
Modified Borntragers test is used for identification of one
of the following drugs.
A.
Digitalis
B.
Dioscorea
C.
Senna
D.
Aloe
111)
The botanical source of Black mustard is ……………
A.
Brassica nigra
B.
Brassia alba
C.
Brassica oleracea
D.
Cassia angustifolia
112)
Amygdaline is a chief constituent of …………
A.
Bitter almond
B.
Wild cherry bark
C.
Rubia
D.
Hypericum
113)
Botanical source of Alexandrian senna is……..
E.
Cassia angustifolia
A.
Cassia acutifolia
B.
Cassia tora
C.
Cassia obtusifolia
114)
Presence of star spots is the characteristic of drug…………..
A.
Senna
B.
Hypericum
C.
Rubia
D.
Rhubarb
115)
……… is a red dye found in the roots
of the madder plant.
A.
Aloe emodin
B.
Alizarin
C.
Sennosides
D.
Hypericin
116)
The substitute for aloe is …………...
A.
Cape aloe
B.
Socotrine aloe
C.
Curacao aloe
D.
Natal aloe
117)
Thioglycosides abundantly found in family.
A.
Cruciferae
B.
Liliaceae
C.
Leguminosae
D.
Rubiaceae
118)
Grignard’s reaction is used for identification of ……………..
A.
Anthracene glycosides
B.
Isothiocyanate glycosides
C.
Cyanogenetic glycosides
D.
Saponin glycosides
119)
……… is the precursor for the
biosynthesis of Amygdalin.
A.
L-Phenyl alanine
B.
Ornithine
C.
Tyrosine
D.
Tryptophan
120)
Rhein is an example of
………
A.
Anthraquinones with carboxylic acid
B.
Anthraquinones without carboxylic acid
C.
Anthrone
D.
Dianthrone
121)
Borntrager’s test involves ……………of glycosides.
A.
Oxidation
B.
Hydrolysis
C.
Reduction
D.
Esterification
122)
Glycosides can be extracted from crude drug using……….
A.
Manskes method
B.
Stass Otto method
C.
Distillation method
D.
pH gradient method
Interactions
with DONO
123)
Milk reduces the absorption of digitalis - Identify the type
of Food-Herb interaction…………
A.
Pharmacokinetic interaction
B.
Pharmacodynamic interaction
C.
Synergistic interaction
D.
Antagonistic interaction
124)
Guar gum decreases absorption of metformin - Identify the type
of herb drug interaction……
A.
Pharmacokinetic interaction
B.
Pharmacodynamic interaction
C.
Synergistic interaction
D.
Antagonistic interaction
125)
When the herb ephedra is taken with MAO inhibitors, one
possible effect is
A.
CNS Stimulation
B.
Depressed MAO inhibitors
C.
Increased risk of arrythmias
D.
Potentiated MAO inhibitors
126)
One herb potentiates the activity of another drug - Identify
the type of herb drug interaction……
A.
Pharmacokinetic interaction
B.
Pharmacodynamic interaction
C.
Synergistic interaction
D.
Antagonistic interaction
127)
When the herb Ma Huang is taken with hypoglycemics, the
result may be
A.
Decreased hypoglycemic effects
B.
Increased fluid retention and potential for increased blood
pressure
C.
Increased bile secretion and loose stool
D.
Increased hypoglycemic effect
128)
When the herb Ginseng is taken with antipsychotic drug, a
possible result is
A.
Stimulated CNS activity
B.
Depressed CNS activity
C.
Coma like states
D.
No impact on CNS activity
129)
When the herb Ginger is taken after chemotherapy, one
possible effect is
A.
Antagonized antihypertensive effect
B.
Weakened immune response
C.
Reduced nausea associated with chemotherapy
D.
Increased nausea
130)
When the herb Garlic is taken with anti-hyperlipidemics, a
possible result is
A.
Potential for additive hypotention
B.
Decreased effectiveness due to increased acid secreation
C.
Additive lipid lowering properties
D.
Reduced nausea
131)
When the herb St. John’s Wort is consumed with opioids or
alcohols, the effect may be ……..
A.
Increased breakthrough bleeding
B.
Enhanced sedative effect
C.
Reduced sedative effect
D.
Increased photosensitivity
Spectroscopy
132)
Citral is …………
A.
Diterpenoid
B.
Monoterpenoid
C.
Triterpenoid
D.
Iridoid
133)
Rutin is ………
A.
Phenylpropanoid
B.
Flavonoid
C.
Alkaloid
D.
Irridoid
134)
Gallic acid is…….
A.
3,4,5-trihydroxybenzoic acid
B.
4,5-dihydroxybenzoic acid
C.
3,4-dihydroxybenzoic acid
D.
3, 5-dihydroxybenzoic acid
135)
UV-VIS spectra of gallic acid in water shows the absorbance
maxima at………
A.
215 nm and 265 nm
B.
205nm
C.
250nm
D.
425nm
136)
UV-VIS spectra of Citral shows the absorbance maxima at………
A.
210nm
B.
236nm
C.
280nm
D.
350nm
137)
The presence of conjugated aldehyde group in the citral is
revealed by…….
A.
UV-spectroscopy
B.
Mass spectroscopy
C.
Proton NMR spectroscopy
D.
C13 NMR spectroscopy
Monograph
of herbal drugs & excipients in Indian Pharmacopoeia
(Included questions from Alkaloids)
138)
A critically reviewed comprehension on Herbal drugs
published in a book for Primary reference is called
A.
Primary standard
B.
Drug Monograph
C.
Herbarium sheet
D.
Review paper
139)
As per Indian Pharmacopoeia, Category under herbal drug
monograph means?
A.
Therapeutic or Prophylactic use
B.
Chemical class of drug
C.
Botanical source of the drug
D.
Description of the drug
140)
The precursor for the biosynthesis of indole alkaloid
is............ …………
A.
Phenylalanine
B.
Tryptophan
C.
Tyrosine
D.
Ornithin
141)
Which of the following drug contains peptide type of
alkaloids?
A.
Digitalis
B.
Dioscorea
C.
Vinka
D.
Ergot
142)
One of the following is a volatile alkaloid
A.
Nicotine
B.
Rutin
C.
Piperine
D.
Caffeine
143)
The botanical name of black pepper is…………
A.
Piper nigrum
B.
Piper longum
C.
Clavicep purpuria
D.
Brassica nigra
144)
Which one of the following drugs is useful in diabetes?
A.
Berberis
B.
Cinchona
C.
Ipecac
D.
Hypericin
145)
Pilocarpine chemical structure contains…………...
A.
Piperidine ring
B.
Lactone ring
C.
Furan ring
D.
Xanthine ring
146)
Glaucoma is treated using…………...
A.
Atropine
B.
Pilocarpine
C.
Quinine
D.
Emetine
147)
Purine alkaloids are identified by……………..
A.
Grignard test
B.
Murexide test
C.
Thallioquin test
D.
Borntragers test
148)
Oxytocic principle present in Vasaka is………
A.
Vasicine
B.
Volatile oil
C.
Adhatodic acid
D.
Betaine
149)
Following is an example of pentacyclic triterpenoid..
A.
Ginseng
B.
Dioscorea
C.
Asparagus
D.
Senna
150)
Quinoline alkaloids are identified by……………..
A.
Grignard test
B.
Murexide test
C.
Thallioquin test
D.
Borntragers test